FRMD3

Across TCGA patient cohorts, FRMD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,923 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FRMD3-associated proteins across cancer lineages are EIF4G1, FRMD3_S429, and UTRN_S1866. Each is linked with FRMD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both FRMD3-to-partner and partner-to-FRMD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD3 versus EIF4G1 in CCRCC, with a Pearson correlation of -0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD3→partner) and Y-score (partner→FRMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	EIF4G1 →	-0.278	-1.187	<.001	<.001	3	6
OV	FRMD3_S429 →	+1.306	+0.728	.002	.003	2	6
HNSC	UTRN_S1866 →	+0.751	+0.649	.001	<.001	3	5
CCRCC	RPS2 →	-0.211	-0.897	<.001	<.001	3	5
LUAD	IQGAP2 →	+0.424	+0.522	<.001	<.001	3	5
PDAC	NES_S1590 →	+1.159	+0.315	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,923 associations by consensus.

FRMD3 vs EIF4G1 — CCRCC

Explore this scatter interactively →