FRMD3

Across TCGA patient cohorts, FRMD3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,826 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FRMD3-associated genes across cancer lineages are FLT1, NTSR1, and RASIP1. Each is linked with FRMD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both FRMD3-to-partner and partner-to-FRMD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD3 versus FLT1 in CCRCC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD3→partner) and Y-score (partner→FRMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FLT1 →	+0.661	+0.596	.004	.002	3	3
LUAD	NTSR1 →	+0.567	+0.504	.004	.008	3	2
CCRCC	RASIP1 →	+0.567	+0.417	<.001	.002	3	2
BRCA	CCL2 →	+1.533	+1.518	.006	.001	3	2
CCRCC	IVNS1ABP →	+0.589	+0.755	<.001	<.001	3	2
CCRCC	TEK →	+1.241	+0.734	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,826 associations by consensus.

FRMD3 vs FLT1 — CCRCC

Explore this scatter interactively →