FRMD3

Across TCGA patient cohorts, FRMD3 protein abundance is significantly associated with the protein abundance of many other proteins, with 8,276 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FRMD3-associated proteins across cancer lineages are FRMD3_S429, ARHGEF15_S109, and ARAP3. Each is linked with FRMD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both FRMD3-to-partner and partner-to-FRMD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD3 versus FRMD3_S429 in BRCA, with a Pearson correlation of 0.93.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD3→partner) and Y-score (partner→FRMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FRMD3_S429 →	+2.413	+1.424	<.001	<.001	3	4
LUAD	ARHGEF15_S109 →	+1.070	+0.799	<.001	<.001	3	3
CCRCC	ARAP3 →	+0.253	+0.529	.001	.006	3	2
BRCA	ARFGEF3_S1991 →	-1.001	-1.251	<.001	<.001	2	3
LUAD	ARHGAP24_S391 →	+0.498	+0.653	<.001	<.001	3	2
GBM	ACIN1_T414 →	+0.455	+0.692	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,276 associations by consensus.

FRMD3 vs FRMD3_S429 — BRCA

Explore this scatter interactively →