FRMD1

Across TCGA patient cohorts, FRMD1 protein abundance is significantly associated with the RNA expression of many other genes, with 440 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FRMD1-associated genes across cancer lineages are PLA2G3, POLDIP3, and HSDL1. Each is linked with FRMD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRMD1-to-partner and partner-to-FRMD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD1 versus PLA2G3 in CCRCC, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD1→partner) and Y-score (partner→FRMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PLA2G3 →	-0.076	-0.714	.001	.008	3	1
CCRCC	POLDIP3 →	-0.341	-0.696	.002	.009	3	1
CCRCC	HSDL1 →	-0.411	-0.708	.007	.008	3	1
CCRCC	UBFD1 →	-0.523	-0.674	<.001	.003	3	1
CCRCC	BFAR →	-0.376	-0.853	<.001	.001	3	1
CCRCC	SPAG1 →	-0.706	-0.624	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 440 associations by consensus.

FRMD1 vs PLA2G3 — CCRCC

Explore this scatter interactively →