FRK

Across TCGA patient cohorts, FRK RNA expression is significantly associated with the protein abundance of many other proteins, with 16,512 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FRK-associated proteins across cancer lineages are NT5DC1, MYO6, and PTPRK. Each is linked with FRK in more than 8 cancer types. Because this analysis shows association rather than direction, both FRK-to-partner and partner-to-FRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRK versus NT5DC1 in OV, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRK→partner) and Y-score (partner→FRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NT5DC1 →	+0.633	+1.515	<.001	<.001	3	9
BRCA	MYO6 →	+0.429	+0.886	.001	.001	3	7
LUAD	PTPRK →	+0.361	+0.516	<.001	<.001	3	5
HNSC	ARFGEF3 →	+0.616	+0.776	<.001	<.001	3	5
OV	MAP7 →	+0.409	+0.830	.009	.005	3	5
LUAD	PARD6B_S11 →	+0.439	+0.454	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,512 associations by consensus.

FRK vs NT5DC1 — OV

Explore this scatter interactively →