FRK

Across TCGA patient cohorts, FRK protein abundance is significantly associated with the RNA expression of many other genes, with 10,429 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FRK-associated genes across cancer lineages are NT5DC1, TPI1P3, and HEBP2. Each is linked with FRK in more than 5 cancer types. Because this analysis shows association rather than direction, both FRK-to-partner and partner-to-FRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRK versus NT5DC1 in OV, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRK→partner) and Y-score (partner→FRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NT5DC1 →	+0.719	+0.787	<.001	<.001	3	6
UCEC	TPI1P3 →	+0.728	+0.605	<.001	.001	3	6
OV	HEBP2 →	+0.649	+0.707	<.001	<.001	3	6
LSCC	ELF3 →	+1.183	+0.614	<.001	<.001	3	5
UCEC	RBM47 →	+0.752	+0.685	<.001	<.001	3	5
OV	PERP →	+1.037	+0.725	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,429 associations by consensus.

FRK vs NT5DC1 — OV

Explore this scatter interactively →