FRK

Across TCGA cell cohorts, FRK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,008 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible FRK-associated GO terms across cancer lineages are Response to molecule of fungal origin, Cellular response to molecule of fungal origin, and Cellular response to alcohol. Each is linked with FRK in more than 12 cancer types. Because this analysis shows association rather than direction, both FRK-to-partner and partner-to-FRK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to molecule of fungal origin grouped by FRK-low versus FRK-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FRK→partner) and Y-score (partner→FRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to molecule of fungal origin →	+1.504	+1.624	<.001	<.001	3	13
URINARY_TRACT	Cellular response to molecule of fungal origin →	+1.504	+1.624	<.001	<.001	3	13
OVARY	Cellular response to alcohol →	+0.096	+1.080	.001	<.001	3	12
STOMACH	Bundle of His cell to Purkinje myocyte communication →	+0.290	+1.728	<.001	<.001	3	12
LIVER	Positive regulation of inflammatory response to wounding →	+0.229	+1.365	.004	.008	3	11
OESOPHAGUS	Negative regulation of mast cell degranulation →	+1.800	+1.629	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,008 associations by consensus.

Response to molecule of fungal origin by FRK expression — URINARY_TRACT

Explore this box plot interactively →