FRGCA

Across TCGA patient cohorts, FRGCA RNA expression is significantly associated with the go_rna of many other GO terms, with 6,910 significant associations in total. LGG shows the largest number of these associations.

The most reproducible FRGCA-associated GO terms across cancer lineages are Galactose catabolic process, L-proline biosynthetic process, and Regulation of DNA-directed DNA polymerase activity. Each is linked with FRGCA in more than 10 cancer types. Because this analysis shows association rather than direction, both FRGCA-to-partner and partner-to-FRGCA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Galactose catabolic process grouped by FRGCA-low versus FRGCA-high in CESC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FRGCA→partner) and Y-score (partner→FRGCA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	Galactose catabolic process →	+0.041	+0.598	<.001	<.001	3	11
PAAD	L-proline biosynthetic process →	+0.052	+0.513	<.001	<.001	3	9
HNSC	Regulation of DNA-directed DNA polymerase activity →	+0.029	+0.133	<.001	<.001	3	9
SARC	Cytoplasmic sequestering of NF-kappaB →	+0.026	+0.149	.001	<.001	3	9
LGG	Pyrimidine deoxyribonucleotide metabolic process →	+0.035	+0.112	<.001	<.001	3	9
LGG	Regulation of DNA-templated DNA replication initiation →	+0.031	+0.076	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,910 associations by consensus.

Galactose catabolic process by FRGCA expression — CESC

Explore this box plot interactively →