FRG2DP

Across TCGA patient cohorts, FRG2DP mutation is significantly associated with the RNA expression of many other genes, with 749 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRG2DP-associated genes across cancer lineages are RNA5SP408, RNA5SP416, and SERPINB8P1. Each is linked with FRG2DP in more than 1 cancer types. Because this analysis shows association rather than direction, both FRG2DP-to-partner and partner-to-FRG2DP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP408 grouped by FRG2DP-low versus FRG2DP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRG2DP→partner) and Y-score (partner→FRG2DP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP408 →	+0.384	+3.186	<.001	.002	3	2
UCEC	RNA5SP416 →	+0.507	+2.738	.002	.003	3	2
LUSC	SERPINB8P1 →	+0.113	+5.191	.001	.003	3	2
SKCM	RNA5SP422 →	+0.283	+7.816	<.001	.008	3	2
UCEC	RASSF1-AS1 →	+0.840	+3.213	<.001	.009	3	1
UCEC	MEX3D →	+0.808	+3.343	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 749 associations by consensus.

RNA5SP408 by FRG2DP expression — UCEC

Explore this box plot interactively →