FRG2DP

Across TCGA patient cohorts, FRG2DP mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRG2DP-associated genes across cancer lineages are GAPDH, JNK2, and Tuberin. Each is linked with FRG2DP in more than 1 cancer types. Because this analysis shows association rather than direction, both FRG2DP-to-partner and partner-to-FRG2DP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by FRG2DP-low versus FRG2DP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRG2DP→partner) and Y-score (partner→FRG2DP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.735	+3.000	.017	.037	3	1
UCEC	JNK2 →	+0.290	+3.000	.011	.037	3	1
UCEC	Tuberin →	+0.448	+2.817	.003	.036	3	1
UCEC	Cyclin-E2 →	+0.191	+3.000	.049	.037	3	1
UCEC	ACC1 →	+0.570	+3.000	.006	.037	2	1
UCEC	Di-Ras3 →	-0.194	-3.000	.024	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

GAPDH by FRG2DP expression — UCEC

Explore this box plot interactively →