FRG2C

Across TCGA pan-cancer cohorts, FRG2C Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FRG2C data layer compared with 23 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FRG2C Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FRG2C expression acts as an unfavorable survival marker.

HNSC, STAD, and SKCM are the cancer types where FRG2C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.177	0.752	<.001	66	view →
STAD	DFS	Median	All	0.134	0.659	<.001	30	view →
SKCM	DFS	Median	II,III,IV	0.290	0.711	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FRG2C–HNSC (OS)

Open the HNSC breakdown →