FRG2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FRG2 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FRG2 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher FRG2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FRG2 expression acts as an unfavorable survival marker.

STAD and LIHC are the cancer types where FRG2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSMedianAll0.2540.689.00624view →
LIHCOSMedianAll0.1050.777<.0019view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration