FRG1HP

Across TCGA pan-cancer cohorts, FRG1HP RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FRG1HP data layer compared with 1 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FRG1HP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FRG1HP expression acts as an unfavorable survival marker, although some lineages such as LUAD and KIRC show a favorable association.

ACC, LUAD, and LIHC are the cancer types where FRG1HP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.176	0.691	<.001	81	view →
LUAD	DFS	Median	III,IV	0.747	0.538	.001	78	view →
LIHC	DFS	Quartile	All	0.423	0.622	<.001	56	view →
KIRC	DFS	Tertile	All	0.727	0.466	<.001	41	view →
BRCA	OS	Tertile	III,IV	0.979	0.862	.004	30	view →
THYM	DFS	Tertile	II,III,IV	0.906	0.544	.002	25	view →
UCS	OS	Tertile	II,III,IV	0.592	0.194	.013	18	view →
KIRP	DFS	Quartile	III,IV	0.182	0.619	.004	13	view →
COAD	OS	Tertile	All	0.781	0.915	.015	13	view →
ESCA	OS	Tertile	IV	0.143	0.679	.024	12	view →
READ	OS	Tertile	II,III,IV	0.981	0.844	.013	10	view →
LGG	OS	Tertile	All	0.821	0.955	.006	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FRG1HP–ACC (DFS)

Open the ACC breakdown →