FRG1

Across TCGA patient cohorts, FRG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,888 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FRG1-associated proteins across cancer lineages are HPF1, RWDD4, and DCTD. Each is linked with FRG1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FRG1-to-partner and partner-to-FRG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRG1 versus HPF1 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRG1→partner) and Y-score (partner→FRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HPF1 →	+0.402	+0.297	<.001	<.001	3	7
OV	RWDD4 →	+0.421	+0.578	<.001	.003	3	4
PDAC	DCTD →	+0.362	+0.313	<.001	.001	3	4
OV	ZNF330 →	+0.500	+0.722	<.001	<.001	3	4
HNSC	UFL1_S458 →	-0.492	-0.751	.002	<.001	3	3
PDAC	MVB12A →	+0.221	+0.305	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,888 associations by consensus.

FRG1 vs HPF1 — GBM

Explore this scatter interactively →