FRG1

Across TCGA patient cohorts, FRG1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,192 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FRG1-associated genes across cancer lineages are KIF20A, CENPU, and HMGB2. Each is linked with FRG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FRG1-to-partner and partner-to-FRG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRG1 versus KIF20A in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRG1→partner) and Y-score (partner→FRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF20A →	+1.215	+0.275	<.001	<.001	3	6
GBM	CENPU →	+0.815	+0.269	<.001	<.001	3	6
UCEC	HMGB2 →	+1.461	+0.299	<.001	<.001	3	6
UCEC	DEPDC1B →	+1.197	+0.254	<.001	<.001	3	6
LSCC	CENPO →	+0.714	+0.340	<.001	<.001	3	5
GBM	ZNF365 →	-0.794	-0.365	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,192 associations by consensus.

FRG1 vs KIF20A — UCEC

Explore this scatter interactively →