FRG1

Across TCGA patient cohorts, FRG1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRG1-associated genes across cancer lineages are GMP and Basophils. Each is linked with FRG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FRG1-to-partner and partner-to-FRG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by FRG1-low versus FRG1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRG1→partner) and Y-score (partner→FRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GMP →	+0.062	+4.264	.003	.024	3	3
UCEC	Basophils →	+0.199	+3.169	.033	.020	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GMP by FRG1 expression — LUSC

Explore this box plot interactively →