FREM1

Across TCGA cell cohorts, FREM1 RNA expression is significantly associated with the RNA expression of many other genes, with 7,233 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FREM1-associated genes across cancer lineages are ALCAM, FOSL1, and PIK3CD. Each is linked with FREM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FREM1-to-partner and partner-to-FREM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FREM1 versus ALCAM in BONE, with a Pearson correlation of -0.54.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FREM1→partner) and Y-score (partner→FREM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	ALCAM →	-2.474	-2.782	<.001	<.001	3	4
BONE	FOSL1 →	-4.326	-3.255	<.001	<.001	3	4
SKIN	PIK3CD →	-1.442	-1.952	.001	.003	2	5
BONE	FSBP →	+1.101	+2.317	<.001	<.001	3	4
BONE	SEMA7A →	-2.571	-2.390	<.001	<.001	3	4
BONE	RNLS →	-1.860	-2.506	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,233 associations by consensus.

FREM1 vs ALCAM — BONE

Explore this scatter interactively →