FRAS1

Across TCGA patient cohorts, FRAS1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,218 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FRAS1-associated genes across cancer lineages are HS6ST1, SERBP1P5, and CRISPLD1. Each is linked with FRAS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FRAS1-to-partner and partner-to-FRAS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRAS1 versus HS6ST1 in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRAS1→partner) and Y-score (partner→FRAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HS6ST1 →	+0.554	+0.648	.002	<.001	3	4
LSCC	SERBP1P5 →	+0.887	+0.753	<.001	<.001	3	4
LSCC	CRISPLD1 →	+1.214	+0.615	<.001	<.001	3	3
LUAD	LRP5L →	+0.483	+0.395	<.001	<.001	3	3
LUAD	ERBB4 →	+0.642	+0.358	.002	<.001	3	3
LUAD	RBP1 →	+0.875	+0.477	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,218 associations by consensus.

FRAS1 vs HS6ST1 — LSCC

Explore this scatter interactively →