FRAS1

Across TCGA patient cohorts, FRAS1 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,917 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FRAS1-associated proteins across cancer lineages are EIF2AK2, NPNT, and RBP1. Each is linked with FRAS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FRAS1-to-partner and partner-to-FRAS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRAS1 versus EIF2AK2 in LSCC, with a Pearson correlation of -0.38.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRAS1→partner) and Y-score (partner→FRAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EIF2AK2 →	-0.378	-0.658	<.001	<.001	3	5
UCEC	NPNT →	+0.623	+0.402	<.001	<.001	3	5
UCEC	RBP1 →	+0.941	+0.657	<.001	<.001	3	5
UCEC	ARVCF →	+0.433	+0.570	<.001	<.001	3	4
UCEC	AASS →	+0.512	+0.452	<.001	<.001	3	4
PDAC	FCHO2 →	-0.265	-0.631	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,917 associations by consensus.

FRAS1 vs EIF2AK2 — LSCC

Explore this scatter interactively →