FRA10AC1

Across TCGA pan-cancer cohorts, FRA10AC1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FRA10AC1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher FRA10AC1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FRA10AC1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, PDAC, and CCRCC are the cancer types where FRA10AC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.937	0.640	<.001	71	view →
PDAC	DFS	Median	All	0.688	0.829	.011	14	view →
CCRCC	OS	Median	II,III,IV	0.067	1.000	.014	12	view →
LUAD	DFS	Median	All	0.757	0.500	.019	5	view →
HNSC	DFS	Median	II,III,IV	0.719	0.875	.034	2	view →
GBM	DFS	Quartile	All	0.443	0.252	.021	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FRA10AC1–LSCC (OS)

Open the LSCC breakdown →