FPR3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FPR3 mutation is significantly associated with the RNA expression of many other genes, with 2,440 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FPR3-associated genes across cancer lineages are RNU4-28P, RNA5SP420, and COX15. Each is linked with FPR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FPR3-to-partner and partner-to-FPR3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FPR3→partner) and Y-score (partner→FPR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU4-28P →+0.251+4.788<.001.00632
CESCRNA5SP420 →+0.346+7.164<.001<.00132
UCECCOX15 →+0.429+2.708.001.00332
UCECCCNB2 →+0.693+2.247.001.00232
UCECRRM1 →+0.893+3.828<.001<.00132
UCECPBK →+0.850+1.858.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,440 associations by consensus.

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