Across TCGA patient cohorts, FPR3 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FPR3-associated genes across cancer lineages are p38-MAPK_pT180_Y182, C-Raf, and Di-Ras3. Each is linked with FPR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FPR3-to-partner and partner-to-FPR3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FPR3→partner) and Y-score (partner→FPR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p38-MAPK_pT180_Y182 →	-0.432	-2.459	.017	.019	3	2
UCEC	C-Raf →	+0.142	+2.584	.013	.010	3	2
UCEC	Di-Ras3 →	-0.121	-1.906	.043	.016	3	2
SKCM	PRAS40_pT246 →	-0.133	-3.309	.028	.009	3	1
SKCM	Syk →	+0.390	+3.186	.038	.009	3	1
UCEC	eIF4G →	+0.318	+2.999	.010	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

FPR3 survival (RNA) · tumor vs normal (RNA) · all FPR3 data types