FPR3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FPR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 967 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FPR3-associated GO terms across cancer lineages are Negative regulation of protein catabolic process, Protein localization to endoplasmic reticulum, and Regulation of stress-activated protein kinase signaling cascade. Each is linked with FPR3 in more than 4 cancer types. Because this analysis shows association rather than direction, both FPR3-to-partner and partner-to-FPR3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FPR3→partner) and Y-score (partner→FPR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaNegative regulation of protein catabolic process →+0.042+0.737<.001<.00135
BLOOD_LeukemiaProtein localization to endoplasmic reticulum →+0.079+0.680<.001.00135
SKINRegulation of stress-activated protein kinase signaling cascade →+0.051+0.110.004.00734
BLOOD_LeukemiaPositive regulation of macroautophagy →+0.045+0.691<.001.00234
BLOOD_LeukemiaRegulation of protein localization to mitochondrion →+0.076+0.524<.001<.00134
BLOOD_LeukemiaRegulation of metallopeptidase activity →+0.130+0.530<.001.00434
Each partner links to its Q-omics profile. Showing the 6 strongest of 967 associations by consensus.

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