FPR1

Across TCGA pan-cancer cohorts, FPR1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FPR1 data layer compared with 26 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher FPR1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FPR1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

READ, LUSC, and ACC are the cancer types where FPR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Median	III,IV	0.121	0.756	<.001	30	view →
LUSC	OS	Median	II,III,IV	0.190	0.632	.014	12	view →
ACC	DFS	Median	All	0.219	0.658	.036	6	view →
UCEC	DFS	Median	All	1.000	0.615	.020	6	view →
BLCA	OS	Median	IV	0.193	0.598	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FPR1–READ (DFS)

Open the READ breakdown →