FPR1

Across TCGA cell cohorts, FPR1 mutation is significantly associated with the RNA expression of many other genes, with 269 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FPR1-associated genes across cancer lineages are GCAT, RPL3, and CTSZ. Each is linked with FPR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FPR1-to-partner and partner-to-FPR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GCAT grouped by FPR1-low versus FPR1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FPR1→partner) and Y-score (partner→FPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GCAT →	+1.076	+3.364	.008	.002	3	1
LARGE_INTESTINE	RPL3 →	+0.576	+3.237	<.001	.003	3	1
LARGE_INTESTINE	CTSZ →	-1.362	-3.278	<.001	.006	3	1
LARGE_INTESTINE	ACRBP →	+0.771	+3.067	.003	.009	3	1
LARGE_INTESTINE	UHRF1BP1L →	+0.535	+3.364	.006	.002	3	1
LARGE_INTESTINE	RIC8B →	+0.490	+3.364	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 269 associations by consensus.

GCAT by FPR1 expression — LARGE_INTESTINE

Explore this box plot interactively →