FPR1

Across TCGA cell cohorts, FPR1 mutation is significantly associated with the mutation status of many other genes, with 4,297 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FPR1-associated genes across cancer lineages are PLCB1, ADAMTS18, and LMTK3. Each is linked with FPR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FPR1-to-partner and partner-to-FPR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLCB1 grouped by FPR1-low versus FPR1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FPR1→partner) and Y-score (partner→FPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PLCB1 →	+5.415	+5.415	.004	.004	1	4
LARGE_INTESTINE	ADAMTS18 →	+2.836	+4.015	<.001	<.001	1	4
LARGE_INTESTINE	LMTK3 →	+2.321	+2.807	<.001	<.001	1	4
LARGE_INTESTINE	PTPRO →	+2.584	+2.471	.001	.001	1	4
SKIN	CDHR2 →	+2.548	+2.641	.008	.008	1	4
LARGE_INTESTINE	RAPGEF4 →	+2.906	+2.632	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,297 associations by consensus.

PLCB1 by FPR1 expression — OVARY

Explore this box plot interactively →