FPGT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FPGT RNA expression is significantly associated with the protein abundance of many other proteins, with 11,171 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FPGT-associated proteins across cancer lineages are WDR75_S779, GNG12, and TSTD1. Each is linked with FPGT in more than 3 cancer types. Because this analysis shows association rather than direction, both FPGT-to-partner and partner-to-FPGT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FPGT versus WDR75_S779 in BRCA, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FPGT→partner) and Y-score (partner→FPGT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAWDR75_S779 →-0.341-0.527.001.00234
BRCAGNG12 →+0.456+0.535.001<.00134
BRCATSTD1 →+0.443+0.465<.001<.00134
LUADCKAP4_S26 →-0.682-0.412<.001<.00134
BRCARSL1D1 →-0.477-0.640<.001<.00134
BRCASHROOM1_S308 →+0.951+0.439<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,171 associations by consensus.

FPGT vs WDR75_S779 — BRCA

Per-sample scatter of FPGT vs WDR75_S779 in BRCA (Pearson r = -0.32).

Explore this scatter interactively →

Exploration