FPGT

Across TCGA patient cohorts, FPGT protein abundance is significantly associated with the RNA expression of many other genes, with 10,297 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FPGT-associated genes across cancer lineages are SCP2, GOLPH3L, and NIT1. Each is linked with FPGT in more than 4 cancer types. Because this analysis shows association rather than direction, both FPGT-to-partner and partner-to-FPGT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FPGT versus SCP2 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FPGT→partner) and Y-score (partner→FPGT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SCP2 →	+0.530	+0.327	<.001	<.001	3	5
BRCA	GOLPH3L →	+0.527	+0.209	<.001	.002	3	5
UCEC	NIT1 →	+0.462	+0.250	.004	.002	3	5
LUAD	SLC44A3 →	+0.688	+0.197	<.001	<.001	3	4
UCEC	ZNF888 →	+0.839	+0.253	<.001	<.001	3	4
BRCA	ARL1 →	+0.478	+0.318	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,297 associations by consensus.

FPGT vs SCP2 — BRCA

Explore this scatter interactively →