FPGT

Across TCGA cell cohorts, FPGT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,759 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FPGT-associated GO terms across cancer lineages are GDP-L-fucose biosynthetic process, GDP-L-fucose salvage, and Nucleotide-sugar metabolic process. Each is linked with FPGT in more than 8 cancer types. Because this analysis shows association rather than direction, both FPGT-to-partner and partner-to-FPGT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GDP-L-fucose biosynthetic process grouped by FPGT-low versus FPGT-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FPGT→partner) and Y-score (partner→FPGT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GDP-L-fucose biosynthetic process →	+0.083	+0.816	.009	.009	3	9
SOFT_TISSUE	GDP-L-fucose salvage →	+0.521	+0.590	.002	<.001	3	9
BONE	Nucleotide-sugar metabolic process →	+0.066	+0.783	<.001	<.001	3	9
BONE	GDP-L-fucose metabolic process →	+0.081	+0.815	.002	.003	3	9
SOFT_TISSUE	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.081	+0.784	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Inositol phosphate metabolic process →	+0.061	+0.765	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,759 associations by consensus.

GDP-L-fucose biosynthetic process by FPGT expression — URINARY_TRACT

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