FPGS

Across TCGA patient cohorts, FPGS RNA expression is significantly associated with the RNA expression of many other genes, with 18,861 significant associations in total. ACC shows the largest number of these associations.

The most reproducible FPGS-associated genes across cancer lineages are GTF3C5, NELFB, and RABL6. Each is linked with FPGS in more than 32 cancer types. Because this analysis shows association rather than direction, both FPGS-to-partner and partner-to-FPGS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FPGS versus GTF3C5 in ACC, with a Pearson correlation of 0.74.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FPGS→partner) and Y-score (partner→FPGS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	GTF3C5 →	+1.044	+0.929	<.001	<.001	3	33
ACC	NELFB →	+1.445	+1.042	<.001	<.001	3	33
ACC	RABL6 →	+1.215	+1.025	<.001	<.001	3	33
ACC	DPM2 →	+1.141	+0.965	<.001	<.001	3	33
ACC	PTGES2 →	+1.019	+1.003	<.001	<.001	3	33
ACC	MED27 →	+1.248	+1.039	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,861 associations by consensus.

FPGS vs GTF3C5 — ACC

Explore this scatter interactively →