FPGS

Across TCGA patient cohorts, FPGS RNA expression is significantly associated with the go_rna of many other GO terms, with 7,157 significant associations in total. THYM shows the largest number of these associations.

The most reproducible FPGS-associated GO terms across cancer lineages are Regulation of G2/MI transition of meiotic cell cycle, Dendritic transport, and Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'. Each is linked with FPGS in more than 17 cancer types. Because this analysis shows association rather than direction, both FPGS-to-partner and partner-to-FPGS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G2/MI transition of meiotic cell cycle grouped by FPGS-low versus FPGS-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FPGS→partner) and Y-score (partner→FPGS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Regulation of G2/MI transition of meiotic cell cycle →	+0.172	+0.686	<.001	<.001	3	18
THYM	Dendritic transport →	-0.042	-0.437	<.001	<.001	3	17
CHOL	Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →	+0.047	+0.701	.001	<.001	2	18
CHOL	U4 snRNA 3'-end processing →	+0.084	+1.004	<.001	<.001	3	17
THYM	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.169	+0.479	<.001	<.001	3	16
READ	tRNA thio-modification →	+0.054	+0.495	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,157 associations by consensus.

Regulation of G2/MI transition of meiotic cell cycle by FPGS expression — THYM

Explore this box plot interactively →