FPGS

Across TCGA patient cohorts, FPGS protein abundance is significantly associated with the protein abundance of many other proteins, with 11,735 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FPGS-associated proteins across cancer lineages are SSNA1, LRSAM1, and STX17. Each is linked with FPGS in more than 4 cancer types. Because this analysis shows association rather than direction, both FPGS-to-partner and partner-to-FPGS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FPGS versus SSNA1 in HNSC, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FPGS→partner) and Y-score (partner→FPGS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SSNA1 →	+0.547	+0.272	<.001	<.001	3	5
HNSC	LRSAM1 →	+0.309	+0.282	<.001	<.001	3	5
LSCC	STX17 →	+0.260	+0.381	<.001	<.001	3	4
HNSC	TBC1D2 →	+0.481	+0.287	<.001	<.001	3	4
GBM	UBTF →	-0.363	-0.333	<.001	.002	3	4
HNSC	GOLGA1 →	+0.249	+0.350	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,735 associations by consensus.

FPGS vs SSNA1 — HNSC

Explore this scatter interactively →