FOXRED1

Across TCGA pan-cancer cohorts, FOXRED1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FOXRED1 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FOXRED1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FOXRED1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

COAD, LSCC, and CCRCC are the cancer types where FOXRED1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	IV	0.565	1.000	.028	6	view →
LSCC	OS	Median	II,III,IV	0.877	0.686	.021	3	view →
CCRCC	DFS	Tertile	All	0.979	0.605	.032	3	view →
HNSC	DFS	Median	III,IV	1.000	0.937	.035	3	view →
GBM	DFS	Median	All	0.306	0.441	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FOXRED1–COAD (DFS)

Open the COAD breakdown →