FOXRED1

Across TCGA cell cohorts, FOXRED1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOXRED1-associated genes across cancer lineages are MSGN1, TAS2R7, and SPRR1A. Each is linked with FOXRED1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXRED1-to-partner and partner-to-FOXRED1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by FOXRED1-low versus FOXRED1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXRED1→partner) and Y-score (partner→FOXRED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.056	+3.345	.007	.007	3	2
BLOOD_Leukemia	TAS2R7 →	+0.021	+4.922	<.001	.009	3	1
BLOOD_Leukemia	SPRR1A →	+0.287	+5.201	<.001	.006	3	1
BLOOD_Leukemia	CNGA2 →	+0.099	+5.539	<.001	.003	3	1
SKIN	TCP10L2 →	+0.139	+5.415	<.001	.004	3	1
LARGE_INTESTINE	MAGEB4 →	+0.016	+4.415	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MSGN1 by FOXRED1 expression — LARGE_INTESTINE

Explore this box plot interactively →