Across TCGA patient cohorts, FOXR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,528 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible FOXR2-associated GO terms across cancer lineages are Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Regulation of mitochondrial gene expression, and Mitotic spindle assembly. Each is linked with FOXR2 in more than 6 cancer types. Because this analysis shows association rather than direction, both FOXR2-to-partner and partner-to-FOXR2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXR2→partner) and Y-score (partner→FOXR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.107	+0.187	<.001	.002	3	7
STAD	Regulation of mitochondrial gene expression →	+0.084	+0.239	<.001	.002	3	7
STAD	Mitotic spindle assembly →	+0.095	+0.119	<.001	.002	3	6
STAD	tRNA 5'-end processing →	+0.087	+0.154	<.001	.003	3	6
STAD	rRNA metabolic process →	+0.103	+0.137	<.001	<.001	3	6
STAD	Positive regulation of cell cycle phase transition →	+0.085	+0.125	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,528 associations by consensus.

Exploration

FOXR2 survival (RNA) · tumor vs normal (RNA) · all FOXR2 data types