FOXR2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FOXR2 mutation is significantly associated with the RNA expression of many other genes, with 2,324 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXR2-associated genes across cancer lineages are MIR4266, LINC02743, and MYOM3-AS1. Each is linked with FOXR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FOXR2-to-partner and partner-to-FOXR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXR2→partner) and Y-score (partner→FOXR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADMIR4266 →+0.267+4.315.002.00733
BRCALINC02743 →+0.496+5.760<.001.00332
CESCMYOM3-AS1 →+0.114+3.874.001.00632
SKCMRASSF1-AS1 →+0.351+2.604.004.00532
SKCMBMS1P20 →+0.417+2.508.005.00132
UCECC22orf39 →+0.415+2.021<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,324 associations by consensus.

Exploration