FOXP4-AS1

Across TCGA pan-cancer cohorts, FOXP4-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated FOXP4-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FOXP4-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FOXP4-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and READ show a favorable association.

KIRC, LIHC, and MESO are the cancer types where FOXP4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.532	0.718	<.001	172	view →
LIHC	DFS	Tertile	All	0.453	0.645	<.001	103	view →
MESO	OS	Quartile	All	0.378	0.773	<.001	93	view →
ACC	OS	Quartile	All	0.425	0.888	.001	76	view →
BRCA	DFS	Median	All	0.932	0.965	<.001	71	view →
OV	OS	Median	All	0.883	0.798	<.001	42	view →
READ	OS	Tertile	III,IV	0.790	0.475	.008	32	view →
LGG	OS	Median	All	0.748	0.866	<.001	31	view →
KIRP	DFS	Median	All	0.959	0.862	.001	23	view →
CESC	DFS	Quartile	All	0.746	0.888	.007	20	view →
LUSC	OS	Tertile	II,III,IV	0.789	0.623	.009	20	view →
LUAD	DFS	Tertile	IV	0.665	0.241	.029	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

FOXP4-AS1–KIRC (OS)

Open the KIRC breakdown →