FOXP3

Across TCGA patient cohorts, FOXP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,445 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FOXP3-associated proteins across cancer lineages are WDFY4, RAC2, and MYO1G. Each is linked with FOXP3 in more than 8 cancer types. Because this analysis shows association rather than direction, both FOXP3-to-partner and partner-to-FOXP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXP3 versus WDFY4 in HNSC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXP3→partner) and Y-score (partner→FOXP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	WDFY4 →	+0.471	+0.674	<.001	<.001	3	9
BRCA	RAC2 →	+0.881	+0.951	<.001	<.001	3	9
BRCA	MYO1G →	+0.604	+1.041	<.001	<.001	3	9
BRCA	LCP2 →	+0.509	+0.956	<.001	<.001	3	9
UCEC	WAS →	+0.575	+0.731	<.001	<.001	3	8
BRCA	ZAP70 →	+0.823	+0.930	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,445 associations by consensus.

FOXP3 vs WDFY4 — HNSC

Explore this scatter interactively →