FOXP1

Across TCGA patient cohorts, FOXP1 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXP1-associated genes across cancer lineages are Caspase-7-cleavedD198, ATM, and Caveolin-1. Each is linked with FOXP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FOXP1-to-partner and partner-to-FOXP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by FOXP1-low versus FOXP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXP1→partner) and Y-score (partner→FOXP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.131	+2.815	.009	.036	3	4
UCEC	ATM →	-0.498	-2.234	<.001	.001	3	3
SKCM	Caveolin-1 →	-0.691	-3.000	.012	.034	3	3
COAD	PCNA →	+0.311	+2.815	.022	.036	3	3
UCEC	EGFR_pY1068 →	-0.175	-1.392	.015	.017	3	2
UCEC	ACC1 →	+0.217	+1.691	.038	.011	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Caspase-7-cleavedD198 by FOXP1 expression — COAD

Explore this box plot interactively →