FOXP1

Across TCGA cell cohorts, FOXP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,624 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FOXP1-associated GO terms across cancer lineages are Regulation of macrophage colony-stimulating factor production, Positive regulation of hydrogen peroxide-mediated programmed cell death, and Negative regulation of androgen receptor signaling pathway. Each is linked with FOXP1 in more than 18 cancer types. Because this analysis shows association rather than direction, both FOXP1-to-partner and partner-to-FOXP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macrophage colony-stimulating factor production grouped by FOXP1-low versus FOXP1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXP1→partner) and Y-score (partner→FOXP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of macrophage colony-stimulating factor production →	+1.808	+1.138	<.001	<.001	3	19
STOMACH	Positive regulation of hydrogen peroxide-mediated programmed cell death →	+0.152	+1.759	<.001	.002	2	18
LUNG_NSCLC_LUAD	Negative regulation of androgen receptor signaling pathway →	+0.118	+1.418	<.001	<.001	3	11
SOFT_TISSUE	Regulation of endothelial tube morphogenesis →	+1.374	+2.026	<.001	<.001	3	11
SKIN	Bone cell development →	-0.181	-1.422	<.001	<.001	3	10
SKIN	Osteoclast development →	-0.181	-1.422	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,624 associations by consensus.

Regulation of macrophage colony-stimulating factor production by FOXP1 expression — LIVER

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