FOXP1

Across TCGA cell cohorts, FOXP1 mutation is significantly associated with the RNA expression of many other genes, with 638 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOXP1-associated genes across cancer lineages are SAXO1, SLC8B1, and H2BC1. Each is linked with FOXP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXP1-to-partner and partner-to-FOXP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAXO1 grouped by FOXP1-low versus FOXP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXP1→partner) and Y-score (partner→FOXP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SAXO1 →	+0.038	+3.041	.001	.001	3	2
LARGE_INTESTINE	SLC8B1 →	+0.971	+3.212	.001	.006	3	2
SOFT_TISSUE	H2BC1 →	+0.433	+5.977	<.001	.001	3	1
SOFT_TISSUE	H2AC1 →	+0.193	+5.977	<.001	.001	3	1
SOFT_TISSUE	KRT6C →	+0.013	+4.930	<.001	.008	3	1
SOFT_TISSUE	KRTAP10-1 →	+0.034	+5.369	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 638 associations by consensus.

SAXO1 by FOXP1 expression — LARGE_INTESTINE

Explore this box plot interactively →