Across TCGA patient cohorts, FOXO6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,994 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FOXO6-associated proteins across cancer lineages are SERPINB1, ZBTB7A, and TNFAIP8. Each is linked with FOXO6 in more than 4 cancer types. Because this analysis shows association rather than direction, both FOXO6-to-partner and partner-to-FOXO6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO6→partner) and Y-score (partner→FOXO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SERPINB1 →	-0.414	-0.715	<.001	<.001	3	5
OV	ZBTB7A →	-0.445	-0.738	.009	.008	3	4
GBM	TNFAIP8 →	-0.642	-0.805	<.001	<.001	3	4
OV	SMARCA1 →	+0.468	+1.001	.001	.001	3	4
UCEC	GMPPB →	-0.344	-0.838	<.001	.001	3	4
OV	NASP →	+0.613	+1.023	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,994 associations by consensus.

Exploration

FOXO6 survival (RNA) · tumor vs normal (RNA) · all FOXO6 data types