Across TCGA patient cohorts, FOXO6 protein abundance is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FOXO6-associated genes across cancer lineages are GLRA2, TTPAL, and SLC34A1. Each is linked with FOXO6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXO6-to-partner and partner-to-FOXO6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO6→partner) and Y-score (partner→FOXO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GLRA2 →	+0.126	+1.195	.007	<.001	3	1
BRCA	TTPAL →	-0.580	-0.853	.005	.006	3	1
BRCA	SLC34A1 →	-0.209	-1.147	.005	.005	3	1
BRCA	FRMPD2B →	+0.817	+0.845	.001	.001	3	1
BRCA	MSGN1 →	+0.150	+0.972	.003	.002	3	1
BRCA	CSRP1 →	+0.754	+0.879	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

FOXO6 survival (RNA) · tumor vs normal (RNA) · all FOXO6 data types