Across TCGA cell cohorts, FOXO6 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible FOXO6-associated genes across cancer lineages are TGM7, GOLGA6L1, and MBD3L2. Each is linked with FOXO6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXO6-to-partner and partner-to-FOXO6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO6→partner) and Y-score (partner→FOXO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	TGM7 →	+0.013	+5.087	<.001	.004	3	1
URINARY_TRACT	GOLGA6L1 →	+0.020	+5.087	<.001	.004	3	1
CNS	MBD3L2 →	+2.479	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

FOXO6 survival (RNA) · tumor vs normal (RNA) · all FOXO6 data types