Across TCGA patient cohorts, FOXO4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,624 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FOXO4-associated proteins across cancer lineages are ERO1A, FOXO4_S241, and RPL4. Each is linked with FOXO4 in more than 5 cancer types. Because this analysis shows association rather than direction, both FOXO4-to-partner and partner-to-FOXO4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO4→partner) and Y-score (partner→FOXO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ERO1A →	-0.608	-0.396	<.001	.005	3	6
BRCA	FOXO4_S241 →	+1.045	+0.834	<.001	<.001	3	6
GBM	RPL4 →	-0.387	-0.696	<.001	<.001	3	5
BRCA	RPL5 →	-0.251	-0.630	<.001	<.001	3	5
BRCA	RPS13 →	-0.309	-0.800	<.001	<.001	3	5
BRCA	HDGFL3 →	+0.591	+0.658	.005	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,624 associations by consensus.

Exploration

FOXO4 survival (RNA) · tumor vs normal (RNA) · all FOXO4 data types