Across TCGA patient cohorts, FOXO4 protein abundance is significantly associated with the RNA expression of many other genes, with 661 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FOXO4-associated genes across cancer lineages are SRPX2, SYTL4, and CBLN1. Each is linked with FOXO4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXO4-to-partner and partner-to-FOXO4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO4→partner) and Y-score (partner→FOXO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SRPX2 →	+1.138	+0.609	.007	.009	3	1
UCEC	SYTL4 →	+1.239	+0.571	.004	.001	3	1
UCEC	CBLN1 →	+1.429	+0.663	.001	.006	3	1
UCEC	CHPT1 →	+0.978	+0.717	.006	<.001	3	1
UCEC	RBM24 →	+2.346	+0.656	<.001	.005	3	1
UCEC	PDE1A →	+1.690	+0.788	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 661 associations by consensus.

Exploration

FOXO4 survival (RNA) · tumor vs normal (RNA) · all FOXO4 data types