Across TCGA cell cohorts, FOXO4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FOXO4-associated genes across cancer lineages are IFNA8, NLRP13, and OR2W1. Each is linked with FOXO4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXO4-to-partner and partner-to-FOXO4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO4→partner) and Y-score (partner→FOXO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IFNA8 →	+0.052	+4.930	<.001	.008	3	1
SOFT_TISSUE	NLRP13 →	+0.006	+4.930	<.001	.008	3	1
SOFT_TISSUE	OR2W1 →	+0.023	+5.977	<.001	.001	3	1
SOFT_TISSUE	PRAMEF18 →	+0.026	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

FOXO4 survival (RNA) · tumor vs normal (RNA) · all FOXO4 data types