FOXO3B

Across TCGA patient cohorts, FOXO3B RNA expression is significantly associated with the protein abundance of many other proteins, with 19,440 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FOXO3B-associated proteins across cancer lineages are POGZ, MVP, and SEC23B. Each is linked with FOXO3B in more than 7 cancer types. Because this analysis shows association rather than direction, both FOXO3B-to-partner and partner-to-FOXO3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXO3B versus POGZ in GBM, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO3B→partner) and Y-score (partner→FOXO3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	POGZ →	+0.298	+0.682	<.001	<.001	3	7
GBM	MVP →	-0.634	-0.618	<.001	<.001	3	7
OV	SEC23B →	-0.324	-0.524	.001	.006	1	8
HNSC	SIN3B →	+0.236	+0.674	<.001	.002	3	6
GBM	ADNP →	+0.378	+0.559	<.001	<.001	3	6
OV	CIB1 →	-0.664	-0.766	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,440 associations by consensus.

FOXO3B vs POGZ — GBM

Explore this scatter interactively →