FOXO3B

Across TCGA patient cohorts, FOXO3B protein abundance is significantly associated with the RNA expression of many other genes, with 1,978 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FOXO3B-associated genes across cancer lineages are USP22, CRK, and MYH10. Each is linked with FOXO3B in more than 2 cancer types. Because this analysis shows association rather than direction, both FOXO3B-to-partner and partner-to-FOXO3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXO3B versus USP22 in LSCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO3B→partner) and Y-score (partner→FOXO3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	USP22 →	+0.624	+0.700	<.001	<.001	3	3
LSCC	CRK →	+0.376	+0.423	.001	.003	3	3
GBM	MYH10 →	+0.928	+0.641	<.001	.001	3	3
LSCC	ZNF286B →	+0.810	+0.603	<.001	<.001	3	3
LSCC	PAFAH1B1 →	+0.378	+0.483	.001	.002	3	3
LUAD	NUP88 →	+0.361	+0.378	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,978 associations by consensus.

FOXO3B vs USP22 — LSCC

Explore this scatter interactively →