FOXO1

Across TCGA patient cohorts, FOXO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,503 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FOXO1-associated proteins across cancer lineages are FOXO1_S287, MSRB3, and FERMT2. Each is linked with FOXO1 in more than 7 cancer types. Because this analysis shows association rather than direction, both FOXO1-to-partner and partner-to-FOXO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXO1 versus FOXO1_S287 in UCEC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXO1→partner) and Y-score (partner→FOXO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO1_S287 →	+0.606	+0.774	<.001	<.001	3	8
BRCA	MSRB3 →	+0.828	+0.906	<.001	<.001	3	7
BRCA	FERMT2 →	+0.634	+0.870	<.001	<.001	3	7
CCRCC	PEAK1 →	+0.270	+0.449	<.001	<.001	3	6
BRCA	TGFB1I1 →	+0.521	+0.653	<.001	<.001	3	6
UCEC	TLN1_S1164 →	+0.878	+0.614	.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,503 associations by consensus.

FOXO1 vs FOXO1_S287 — UCEC

Explore this scatter interactively →